TXNRD1 Antikörper

Produktnummer ABIN7259296

Produktdetails anti-TXNRD1 Antikörper

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human TXNRD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Andere Bezeichnung: TXNRD1 (TXNRD1 Produkte)

Synonyme: TrxR1 antikoerper, cb682 antikoerper, fb83a08 antikoerper, wu:fb83a08 antikoerper, GB14972 antikoerper, MGC85342 antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, T32G6.20 antikoerper, T32G6_20 antikoerper, GRIM-12 antikoerper, TR antikoerper, TR1 antikoerper, TRXR1 antikoerper, TXNR antikoerper, Tr antikoerper, thioredoxin reductase 1 antikoerper, thioredoxin reductase 1 L homeolog antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, ThioRedoXin Reductase antikoerper, TXNRD1 antikoerper, txnrd1 antikoerper, Trxr-1 antikoerper, txnrd1.L antikoerper, NTRC antikoerper, trxr-1 antikoerper, Txnrd1 antikoerper

Hintergrund: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Gen-ID: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis