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CD59 Antikörper

CD59 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259438
  • Target Alle CD59 Antikörper anzeigen
    CD59
    Reaktivität
    • 140
    • 13
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 89
    • 72
    • 6
    • 4
    Kaninchen
    Klonalität
    • 94
    • 74
    • 1
    Polyklonal
    Konjugat
    • 76
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD59 Antikörper ist unkonjugiert
    Applikation
    • 99
    • 67
    • 44
    • 40
    • 31
    • 27
    • 25
    • 15
    • 14
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human CD59
    Isotyp
    IgG
    Top Product
    Discover our top product CD59 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CD59
    Andere Bezeichnung
    CD59 (CD59 Produkte)
    Synonyme
    16.3A5 antikoerper, 1F5 antikoerper, EJ16 antikoerper, EJ30 antikoerper, EL32 antikoerper, G344 antikoerper, HRF-20 antikoerper, HRF20 antikoerper, MAC-IP antikoerper, MACIF antikoerper, MEM43 antikoerper, MIC11 antikoerper, MIN1 antikoerper, MIN2 antikoerper, MIN3 antikoerper, MIRL antikoerper, MSK21 antikoerper, p18-20 antikoerper, Cd59a antikoerper, Cd59b antikoerper, MACIP antikoerper, CD59 molecule (CD59 blood group) antikoerper, CD59 molecule antikoerper, CD59 antikoerper, Cd59 antikoerper
    Hintergrund
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    Gen-ID
    966
    UniProt
    P13987
    Pathways
    Komplementsystem
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