NAIP Antikörper

Produktnummer ABIN7259464

Produktdetails anti-NAIP Antikörper

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human NAIP (NP_075043.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Andere Bezeichnung: NAIP (NAIP Produkte)

Synonyme: BIRC1 antikoerper, NLRB1 antikoerper, psiNAIP antikoerper, AV364616 antikoerper, Birc1a antikoerper, D13Lsd1 antikoerper, Naip antikoerper, Naip-rs1 antikoerper, NLR family apoptosis inhibitory protein antikoerper, NLR family, apoptosis inhibitory protein 1 antikoerper, NAIP antikoerper, Naip1 antikoerper

Hintergrund: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 160 kDa

Calculated_MW: 159 kDa

Gen-ID: 4671

UniProt: Q13075

Pathways: Apoptose, Inflammasome