Complement Factor B Antikörper
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- Target Alle Complement Factor B (CFB) Antikörper anzeigen
- Complement Factor B (CFB)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Complement Factor B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human Complement Factor B (NP_001701.2).
- Isotyp
- IgG
- Top Product
- Discover our top product CFB Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Complement Factor B (CFB)
- Andere Bezeichnung
- Complement Factor B (CFB Produkte)
- Hintergrund
- This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
- Molekulargewicht
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Observed_MW: 86 kDa
Calculated_MW: 68 kDa/85 kDa
- Gen-ID
- 629
- UniProt
- P00751
- Pathways
- Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
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