MED1 Antikörper

Produktnummer ABIN7259644

Produktdetails anti-MED1 Antikörper

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human MED1 (NP_004765.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MED1

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Andere Bezeichnung: MED1 (MED1 Produkte)

Synonyme: CRSP1 antikoerper, CRSP200 antikoerper, DRIP205 antikoerper, DRIP230 antikoerper, PBP antikoerper, PPARBP antikoerper, PPARGBP antikoerper, RB18A antikoerper, TRAP220 antikoerper, TRIP2 antikoerper, CRSP-1 antikoerper, MED1 antikoerper, pbp antikoerper, nbr1 antikoerper, crsp1 antikoerper, rb18a antikoerper, trip2 antikoerper, pparbp antikoerper, crsp200 antikoerper, drip205 antikoerper, drip230 antikoerper, ppargbp antikoerper, trap220 antikoerper, CG7162 antikoerper, Dmel\\CG7162 antikoerper, Med1 antikoerper, Med1/SOP3/TRAP220 antikoerper, Trap220 antikoerper, dTRAP220 antikoerper, AI480703 antikoerper, CRSP210 antikoerper, Pparbp antikoerper, l11Jus15 antikoerper, RGD1559552 antikoerper, mediator complex subunit 1 antikoerper, calcitonin-related polypeptide beta antikoerper, Mediator complex subunit 1 antikoerper, mediator of RNA polymerase II transcription subunit 1 antikoerper, MED1 antikoerper, CALCB antikoerper, med1 antikoerper, Med1 antikoerper

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Molekulargewicht:

Observed_MW: 160 kDa

Calculated_MW: 61 kDa/168 kDa

Gen-ID: 5469

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha