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FKBP1A Antikörper

FKBP1A Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259707
  • Target Alle FKBP1A Antikörper anzeigen
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Reaktivität
    • 58
    • 28
    • 20
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 56
    • 9
    Kaninchen
    Klonalität
    • 48
    • 17
    Polyklonal
    Konjugat
    • 29
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser FKBP1A Antikörper ist unkonjugiert
    Applikation
    • 36
    • 22
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human FKBP1A (NP_463460.1).
    Isotyp
    IgG
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  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Andere Bezeichnung
    FKBP1A (FKBP1A Produkte)
    Hintergrund
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
    Gen-ID
    2280
    UniProt
    P62942
    Pathways
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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