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POLH Antikörper

POLH Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259837
  • Target Alle POLH Antikörper anzeigen
    POLH (Polymerase (DNA Directed), eta (POLH))
    Reaktivität
    • 42
    • 11
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 42
    • 3
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLH Antikörper ist unkonjugiert
    Applikation
    • 32
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human DNA polymerase eta (NP_006493.1).
    Isotyp
    IgG
    Top Product
    Discover our top product POLH Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    POLH (Polymerase (DNA Directed), eta (POLH))
    Andere Bezeichnung
    DNA polymerase eta (POLH Produkte)
    Synonyme
    POLH antikoerper, fc50a12 antikoerper, wu:fc50a12 antikoerper, zgc:136881 antikoerper, zgc:152642 antikoerper, RAD30 antikoerper, RAD30A antikoerper, XP-V antikoerper, XPV antikoerper, polymerase (DNA directed), eta S homeolog antikoerper, DNA polymerase eta antikoerper, polymerase (DNA directed), eta antikoerper, putative DNA polymerase eta antikoerper, polymerase (DNA directed), eta (RAD 30 related) antikoerper, polh.S antikoerper, POLH antikoerper, polh antikoerper, Tb10.70.6190 antikoerper, LINJ_21_0690 antikoerper, Polh antikoerper, LOC100443019 antikoerper
    Hintergrund
    This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 70 kDa

    Calculated_MW: 46 kDa/78 kDa

    Gen-ID
    5429
    UniProt
    Q9Y253
    Pathways
    DNA Reparatur
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