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DDB2 Antikörper

DDB2 Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7009799
  • Target Alle DDB2 Antikörper anzeigen
    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
    Reaktivität
    • 37
    • 16
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 36
    • 3
    Kaninchen
    Klonalität
    • 27
    • 12
    Polyklonal
    Konjugat
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser DDB2 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human DDB2 (NP_000098.1).
    Isotyp
    IgG
    Top Product
    Discover our top product DDB2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
    Andere Bezeichnung
    DDB2 (DDB2 Produkte)
    Synonyme
    2610043A19Rik antikoerper, si:dkey-45f10.3 antikoerper, DDBB antikoerper, UV-DDB2 antikoerper, damage specific DNA binding protein 2 antikoerper, damage-specific DNA binding protein 2 antikoerper, DDB2 antikoerper, ddb2 antikoerper, Ddb2 antikoerper
    Hintergrund
    This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 48 kDa

    Calculated_MW: 17 kDa/26 kDa/40 kDa/47 kDa

    Gen-ID
    1643
    UniProt
    Q92466
    Pathways
    DNA Reparatur
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