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PSMC2 Antikörper

PSMC2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7260033
  • Target Alle PSMC2 Antikörper anzeigen
    PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
    Reaktivität
    • 39
    • 33
    • 31
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 8
    Kaninchen
    Klonalität
    • 46
    • 7
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMC2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 23
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PSMC2 (NP_002794.1).
    Isotyp
    IgG
    Top Product
    Discover our top product PSMC2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
    Andere Bezeichnung
    PSMC2 (PSMC2 Produkte)
    Synonyme
    xMSS1 antikoerper, psmc2 antikoerper, DDBDRAFT_0168337 antikoerper, DDBDRAFT_0232966 antikoerper, DDB_0168337 antikoerper, DDB_0232966 antikoerper, MSS1 antikoerper, Nbla10058 antikoerper, S7 antikoerper, NCU02840.1 antikoerper, zgc:63995 antikoerper, proteasome 26S subunit, ATPase 2 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 2 antikoerper, 26S protease regulatory subunit 7 antikoerper, proteasome 26S subunit, ATPase 2 antikoerper, regulatory particle, ATPase-like-1 antikoerper, psmc2.L antikoerper, psmc2 antikoerper, psmC2 antikoerper, PSMC2 antikoerper, rpt-1 antikoerper, GL50803_21331 antikoerper, EHI_080890 antikoerper, UREG_01412 antikoerper, PITG_10169 antikoerper, Psmc2 antikoerper, GL50803_86683 antikoerper, Tsp_09237 antikoerper
    Hintergrund
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht

    Observed_MW: 49 kDa

    Calculated_MW: 33 kDa/48 kDa

    Gen-ID
    5701
    UniProt
    P35998
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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