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Dynamitin Antikörper

DCTN2 Reaktivität: Human, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7260303
  • Target Alle Dynamitin (DCTN2) Antikörper anzeigen
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Reaktivität
    • 42
    • 36
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 49
    • 6
    • 3
    Kaninchen
    Klonalität
    • 54
    • 4
    Polyklonal
    Konjugat
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dynamitin Antikörper ist unkonjugiert
    Applikation
    • 46
    • 17
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human DCTN2 (NP_006391.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Andere Bezeichnung
    DCTN2 (DCTN2 Produkte)
    Hintergrund
    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 44 kDa

    Calculated_MW: 44 kDa

    Gen-ID
    10540
    UniProt
    Q13561
    Pathways
    M Phase, Ribonucleoprotein Complex Subunit Organization
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