Dynamitin Antikörper
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- Target Alle Dynamitin (DCTN2) Antikörper anzeigen
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Dynamitin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human DCTN2 (NP_006391.1).
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Andere Bezeichnung
- DCTN2 (DCTN2 Produkte)
- Hintergrund
- This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 44 kDa
Calculated_MW: 44 kDa
- Gen-ID
- 10540
- UniProt
- Q13561
- Pathways
- M Phase, Ribonucleoprotein Complex Subunit Organization
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