CBX3 Antikörper

Produktnummer ABIN7260333

Produktdetails anti-CBX3 Antikörper

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Spezifität: This antibody ist KO validated.

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Güteklasse: KO Validated

Immunogen: Recombinant fusion protein of human CBX3 (NP_009207.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Andere Bezeichnung: CBX3 (CBX3 Produkte)

Synonyme: HECH antikoerper, HP1-GAMMA antikoerper, HP1Hs-gamma antikoerper, Hp1-gamma antikoerper, HP1g antikoerper, M32 antikoerper, cbx3 antikoerper, cbx3a antikoerper, xhp1g antikoerper, wu:fb61b02 antikoerper, zgc:153397 antikoerper, chromobox 3 antikoerper, chromobox 3 L homeolog antikoerper, chromobox protein homolog 3 pseudogene antikoerper, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antikoerper, CBX3 antikoerper, Cbx3 antikoerper, cbx3.L antikoerper, LOC100355282 antikoerper, cbx3a antikoerper

Hintergrund: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Molekulargewicht:

Observed_MW: 23 kDa

Calculated_MW: 20 kDa

Gen-ID: 11335

UniProt: Q13185