PSMC4 Antikörper

Produktnummer ABIN7010113

Produktdetails anti-PSMC4 Antikörper

Target: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PSMC4 (NP_006494.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PSMC4

Target: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Andere Bezeichnung: PSMC4 (PSMC4 Produkte)

Synonyme: NCU02260.1 antikoerper, AO090003000692 antikoerper, DDBDRAFT_0188209 antikoerper, DDBDRAFT_0191435 antikoerper, DDB_0188209 antikoerper, DDB_0191435 antikoerper, MIP224 antikoerper, RPT3 antikoerper, S6 antikoerper, TBP-7 antikoerper, TBP7 antikoerper, CIP21 antikoerper, Tbp7 antikoerper, 26S protease regulatory subunit 6B antikoerper, regulatory particle, ATPase-like-3 antikoerper, 26S proteasome regulatory subunit 6B antikoerper, proteasome 26S subunit, ATPase 4 antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase, 4 antikoerper, LOC732870 antikoerper, rpt-3 antikoerper, ATEG_04674 antikoerper, LELG_01296 antikoerper, HCAG_00039 antikoerper, LOC5568998 antikoerper, GL50803_7950 antikoerper, EDI_044950 antikoerper, AOR_1_1218154 antikoerper, PTRG_03339 antikoerper, psmC4 antikoerper, prs6b antikoerper, LOC100381342 antikoerper, psmc4 antikoerper, PSMC4 antikoerper, Psmc4 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht:

Observed_MW: 47 kDa

Calculated_MW: 43 kDa/47 kDa

Gen-ID: 5704

UniProt: P43686

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway