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PRNP Antikörper

PRNP Reaktivität: Human, Ratte, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7260569
  • Target Alle PRNP Antikörper anzeigen
    PRNP (Prion Protein (PRNP))
    Reaktivität
    • 85
    • 33
    • 25
    • 12
    • 11
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 85
    • 17
    • 2
    • 1
    Kaninchen
    Klonalität
    • 77
    • 28
    Polyklonal
    Konjugat
    • 46
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser PRNP Antikörper ist unkonjugiert
    Applikation
    • 53
    • 32
    • 27
    • 26
    • 18
    • 14
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PRNP (NP_001073592.1).
    Isotyp
    IgG
    Top Product
    Discover our top product PRNP Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PRNP (Prion Protein (PRNP))
    Andere Bezeichnung
    PRNP (PRNP Produkte)
    Hintergrund
    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
    Molekulargewicht

    Observed_MW: 20-30 kDa

    Calculated_MW: 8 kDa/26 kDa/27 kDa

    Gen-ID
    5621
    UniProt
    P04156
    Pathways
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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