Claudin 11 Antikörper

Produktnummer ABIN7260581

Produktdetails anti-Claudin 11 Antikörper

Target: Claudin 11 (CLDN11)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 11 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CLDN11 (NP_005593.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:20-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Claudin 11

Target: Claudin 11 (CLDN11)

Andere Bezeichnung: CLDN11 (CLDN11 Produkte)

Synonyme: cldn11 antikoerper, fb97c11 antikoerper, wu:fb97c11 antikoerper, claudin-11 antikoerper, CLDN11 antikoerper, Claudin-11 antikoerper, DKFZp459H2322 antikoerper, OSP antikoerper, OTM antikoerper, Claudin11 antikoerper, Osp antikoerper, Otm antikoerper, claudin 11b antikoerper, claudin 11 antikoerper, cldn11b antikoerper, CLDN11 antikoerper, Cldn11 antikoerper

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gen-ID: 5010

UniProt: O75508

Pathways: Hepatitis C