EB1 antikoerper, 5530600P05Rik antikoerper, AI462499 antikoerper, AI504412 antikoerper, AW260097 antikoerper, BIM1p antikoerper, D2Ertd459e antikoerper, Eb1 antikoerper, MAPRE1 antikoerper, mapre1l antikoerper, wu:fi33c06 antikoerper, zgc:55428 antikoerper, zgc:77807 antikoerper, mapre1 antikoerper, wu:fa01e12 antikoerper, wu:fc23e11 antikoerper, zgc:85755 antikoerper, MGC52508 antikoerper, eb1 antikoerper, xEB1B antikoerper, Mapre3 antikoerper, microtubule associated protein RP/EB family member 1 antikoerper, microtubule-associated protein, RP/EB family, member 1 antikoerper, microtubule-associated protein, RP/EB family, member 1a antikoerper, microtubule-associated protein, RP/EB family, member 1b antikoerper, microtubule associated protein RP/EB family member 1 L homeolog antikoerper, microtubule associated protein RP/EB family member 1 S homeolog antikoerper, MAPRE1 antikoerper, Mapre1 antikoerper, mapre1a antikoerper, mapre1b antikoerper, mapre1.L antikoerper, mapre1.S antikoerper
Hintergrund
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.