MAPKBP1 Antikörper

Produktnummer ABIN7260601

Produktdetails anti-MAPKBP1 Antikörper

Target: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKBP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human MAPKBP1 (NP_001122080.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPKBP1

Target: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Andere Bezeichnung: MAPKBP1 (MAPKBP1 Produkte)

Synonyme: MGC83682 antikoerper, JNKBP-1 antikoerper, 2810483F24Rik antikoerper, AW123212 antikoerper, Jnkbp1 antikoerper, mKIAA0596 antikoerper, mitogen-activated protein kinase binding protein 1 L homeolog antikoerper, mitogen-activated protein kinase binding protein 1 antikoerper, mitogen activated protein kinase binding protein 1 antikoerper, mapkbp1.L antikoerper, MAPKBP1 antikoerper, Mapkbp1 antikoerper

Hintergrund: This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.

Gen-ID: 23005

UniProt: O60336