Cullin 2 Antikörper
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- Target Alle Cullin 2 (CUL2) Antikörper anzeigen
- Cullin 2 (CUL2)
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cullin 2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CUL2 (NP_001185708.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CUL2 Primärantikörper
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anti-Cullin 2 (CUL2) (C-Term) antibody
CUL2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 18-182) antibodyCUL2 Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 4-CUL unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 591-742) antibodyCUL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 150-179), (N-Term) antibodyCUL2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB33843 unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4G11 unconjugated
anti-Cullin 2 (CUL2) (AA 40-310) antibodyCUL2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyVerified CUL2 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Cullin 2 (CUL2)
- Andere Bezeichnung
- CUL2 (CUL2 Produkte)
- Hintergrund
- Human CUL2 is an ortholog of nematode cul2. Michel and Xiong (1998) identified human CUL2 cDNAs and reported that the predicted protein is 745 amino acids long.Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, whicHuman, Mouseediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
- Gen-ID
- 8453
- UniProt
- Q13617
- Pathways
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom
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