EIF4G2 Antikörper

Produktnummer ABIN7260709

Produktdetails anti-EIF4G2 Antikörper

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4G2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human EIF4G2 (NP_001409.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Andere Bezeichnung: EIF4G2 (EIF4G2 Produkte)

Synonyme: AAG1 antikoerper, DAP5 antikoerper, NAT1 antikoerper, P97 antikoerper, NAT1B antikoerper, eif4g2 antikoerper, hm:zeh1307 antikoerper, wu:fa14h01 antikoerper, wu:fb44h01 antikoerper, wu:fb59c06 antikoerper, wu:fc21b05 antikoerper, EIF4G2 antikoerper, AA589388 antikoerper, DAP-5 antikoerper, E130105L11Rik antikoerper, Nat1 antikoerper, Natm1 antikoerper, p97 antikoerper, NAT1A antikoerper, im:7148615 antikoerper, wu:fb81f07 antikoerper, wu:fb82b06 antikoerper, wu:fb98h08 antikoerper, dap5 antikoerper, eif4g2.L antikoerper, nat1 antikoerper, eukaryotic translation initiation factor 4 gamma 2 antikoerper, eukaryotic translation initiation factor 4, gamma 2b antikoerper, eukaryotic translation initiation factor 4, gamma 2 antikoerper, eukaryotic translation initiation factor 4 gamma, 2 antikoerper, eIF4G-related protein NAT1 antikoerper, eukaryotic translation initiation factor 4, gamma 2a antikoerper, eukaryotic translation initiation factor 4 gamma, 2 S homeolog antikoerper, EIF4G2 antikoerper, eif4g2b antikoerper, Eif4g2 antikoerper, nat1 antikoerper, eif4g2a antikoerper, eif4g2.S antikoerper

Hintergrund: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gen-ID: 1982

UniProt: P78344