Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CSTB Antikörper

CSTB Reaktivität: Human, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7260869
  • Target Alle CSTB Antikörper anzeigen
    CSTB (Cystatin B (Stefin B) (CSTB))
    Reaktivität
    • 85
    • 20
    • 20
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Ratte
    Wirt
    • 85
    • 17
    • 1
    • 1
    Kaninchen
    Klonalität
    • 84
    • 19
    Polyklonal
    Konjugat
    • 48
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSTB Antikörper ist unkonjugiert
    Applikation
    • 64
    • 37
    • 35
    • 15
    • 13
    • 13
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CSTB (NP_000091.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CSTB Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CSTB (Cystatin B (Stefin B) (CSTB))
    Andere Bezeichnung
    CSTB (CSTB Produkte)
    Hintergrund
    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.
    Molekulargewicht

    Observed_MW: 14 kDa

    Calculated_MW: 11 kDa

    Gen-ID
    1476
    UniProt
    P04080
    Pathways
    Response to Water Deprivation
Sie sind hier:
Kundenservice