HBEGF Antikörper (AA 51-150)
-
- Target Alle HBEGF Antikörper anzeigen
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
-
Bindungsspezifität
- AA 51-150
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser HBEGF Antikörper ist unkonjugiert
-
Applikation
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
- Isotyp
- IgG
-
-
- Applikationshinweise
-
ELISA 1:500-1000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
-
Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).
: "
-
Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).
-
- Target
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- Andere Bezeichnung
- HB-EGF (HBEGF Produkte)
- Hintergrund
-
Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF
Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
- Gen-ID
- 1839
- UniProt
- Q99075
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
-