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HBEGF Antikörper (AA 51-150)

HBEGF Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN701050
  • Target Alle HBEGF Antikörper anzeigen
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Bindungsspezifität
    • 15
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 74
    • 19
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 68
    • 9
    Kaninchen
    Klonalität
    • 66
    • 10
    • 1
    Polyklonal
    Konjugat
    • 25
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser HBEGF Antikörper ist unkonjugiert
    Applikation
    • 34
    • 28
    • 25
    • 15
    • 13
    • 10
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).

  • Target
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Andere Bezeichnung
    HB-EGF (HBEGF Produkte)
    Synonyme
    hbegf antikoerper, zgc:165443 antikoerper, HBEGF antikoerper, zgc:175091 antikoerper, DTR antikoerper, DTS antikoerper, DTSF antikoerper, HEGFL antikoerper, Dtr antikoerper, GFHB antikoerper, Hb-egf antikoerper, Hegfl antikoerper, AW047313 antikoerper, Dts antikoerper, HB-EGF antikoerper, heparin-binding EGF-like growth factor b antikoerper, heparin binding EGF like growth factor antikoerper, Heparin-binding EGF-like growth factor antikoerper, heparin-binding EGF-like growth factor a antikoerper, heparin-binding EGF-like growth factor antikoerper, hbegfb antikoerper, HBEGF antikoerper, hbegf antikoerper, hbegfa antikoerper, Hbegf antikoerper
    Hintergrund

    Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    Gen-ID
    1839
    UniProt
    Q99075
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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