Glutaredoxin 1 Antikörper

Produktnummer ABIN7261263

Produktdetails anti-Glutaredoxin 1 Antikörper

Target: Glutaredoxin 1 (GRX1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human GLRX (NP_001112362.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Andere Bezeichnung: GLRX (GRX1 Produkte)

Substanzklasse: Viral Protein

Hintergrund: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gen-ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis