Glutaredoxin 1 Antikörper

Produktnummer ABIN7261263

Produktdetails anti-Glutaredoxin 1 Antikörper

Target: Glutaredoxin 1 (GRX1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human GLRX (NP_001112362.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Andere Bezeichnung: GLRX (GRX1 Produkte)

Synonyme: Glrx1 antikoerper, Grx antikoerper, grx antikoerper, wu:fc38f02 antikoerper, zgc:103707 antikoerper, GLRXL antikoerper, Grx1 antikoerper, TTase antikoerper, C86710 antikoerper, D13Wsu156e antikoerper, grx1 antikoerper, GLRX antikoerper, GRX antikoerper, GRX1 antikoerper, GLRX1 antikoerper, TTF antikoerper, glrx antikoerper, glutaredoxin antikoerper, glutaredoxin (thioltransferase) antikoerper, glutaredoxin Grx1 antikoerper, NrdH-redoxin antikoerper, Uncharacterized monothiol glutaredoxin F10D7.3 antikoerper, glutaredoxin-1 (Grx1) antikoerper, temporal expression: late antikoerper, glutaredoxin L homeolog antikoerper, Glrx antikoerper, glrx antikoerper, GLRX antikoerper, grx1 antikoerper, AF_RS07750 antikoerper, F10D7.3 antikoerper, AFUA_1G06100 antikoerper, NT01EI_2528 antikoerper, O2L antikoerper, glrx.L antikoerper

Substanzklasse: Viral Protein

Hintergrund: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gen-ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis