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GTF2H2 Antikörper

GTF2H2 Reaktivität: Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7261267
  • Target Alle GTF2H2 Antikörper anzeigen
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    Reaktivität
    • 38
    • 18
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 32
    • 6
    Kaninchen
    Klonalität
    • 33
    • 5
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser GTF2H2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 12
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human GTF2H2 (NP_001506.1).
    Isotyp
    IgG
    Top Product
    Discover our top product GTF2H2 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    Andere Bezeichnung
    GTF2H2 (GTF2H2 Produkte)
    Synonyme
    44kDa antikoerper, BTF2 p44 antikoerper, BTF2-p44 antikoerper, Btf2p44 antikoerper, p44 antikoerper, BTF2 antikoerper, BTF2P44 antikoerper, T-BTF2P44 antikoerper, TFIIH antikoerper, general transcription factor II H, polypeptide 2 antikoerper, general transcription factor IIH subunit 2 antikoerper, general transcription factor IIH, polypeptide 2, 44kDa antikoerper, Gtf2h2 antikoerper, GTF2H2 antikoerper
    Hintergrund
    This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.
    Gen-ID
    2966
    UniProt
    Q13888
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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