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HUS1 Antikörper

HUS1 Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7261357
  • Target Alle HUS1 Antikörper anzeigen
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Reaktivität
    • 51
    • 28
    • 14
    Human, Maus
    Wirt
    • 62
    • 4
    Kaninchen
    Klonalität
    • 65
    • 1
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HUS1 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 27
    • 13
    • 13
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human HUS1 (NP_004498.1).
    Isotyp
    IgG
    Top Product
    Discover our top product HUS1 Primärantikörper
  • Applikationshinweise
    IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Andere Bezeichnung
    HUS1 (HUS1 Produkte)
    Synonyme
    hHUS1 antikoerper, mHus1 antikoerper, XHus1 antikoerper, hus1 antikoerper, HUS1 checkpoint clamp component antikoerper, checkpoint clamp complex protein Hus1 antikoerper, HUS1 checkpoint clamp component L homeolog antikoerper, HUS1 antikoerper, Hus1 antikoerper, hus1 antikoerper, hus1.L antikoerper
    Hintergrund
    The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
    Gen-ID
    3364
    UniProt
    O60921
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