fb43c01 antikoerper, wu:fb43c01 antikoerper, zgc:55788 antikoerper, rab6 antikoerper, MGC53077 antikoerper, rab6b antikoerper, rab6a' antikoerper, MGC76176 antikoerper, LOC692966 antikoerper, RAB6 antikoerper, 2610028L11Rik antikoerper, AA419671 antikoerper, Rab6 antikoerper, RCO4-3 antikoerper, Rab6b antikoerper, RAB6A, member RAS oncogene family antikoerper, RAB6A, member RAS oncogene family S homeolog antikoerper, ras small monomeric GTPase Rab6 antikoerper, ras-related protein Rab-6A antikoerper, rab6a antikoerper, rab6a.S antikoerper, LOC692966 antikoerper, RAB6A antikoerper, Rab6a antikoerper
Hintergrund
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.