ING3 Antikörper
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- Target Alle ING3 Antikörper anzeigen
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ING3 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ING3 (NP_938008.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ING3 Primärantikörper
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- Applikationshinweise
- IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- Andere Bezeichnung
- ING3 (ING3 Produkte)
- Synonyme
- ING3 antikoerper, Eaf4 antikoerper, ING2 antikoerper, MEAF4 antikoerper, p47ING3 antikoerper, 1300013A07Rik antikoerper, P47ING3 antikoerper, zgc:56327 antikoerper, inhibitor of growth family member 3 antikoerper, inhibitor of growth family, member 3 antikoerper, inhibitor of growth protein 3 antikoerper, inhibitor of growth family member 3 L homeolog antikoerper, ING3 antikoerper, Ing3 antikoerper, CpipJ_CPIJ009396 antikoerper, ing3 antikoerper, ing3.L antikoerper
- Hintergrund
- The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
- Gen-ID
- 54556
- UniProt
- Q9NXR8
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