LIMS1 Antikörper

Produktnummer ABIN7011076

Produktdetails anti-LIMS1 Antikörper

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human LIMS1 (NP_001180417.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LIMS1

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Andere Bezeichnung: LIMS1 (LIMS1 Produkte)

Synonyme: PINCH antikoerper, PINCH-1 antikoerper, PINCH1 antikoerper, Pinch1 antikoerper, RGD1560732 antikoerper, LIMS3 antikoerper, LIMS3L antikoerper, 2310016J22Rik antikoerper, 4921524A02Rik antikoerper, AI507642 antikoerper, AU021743 antikoerper, AW551584 antikoerper, C430041B13Rik antikoerper, Lims1l antikoerper, LIM zinc finger domain containing 1 antikoerper, LIM and senescent cell antigen-like domains 1 antikoerper, LIMS1 antikoerper, Lims1 antikoerper

Hintergrund: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 40 kDa

Calculated_MW: 37 kDa/38 kDa/41 kDa/44 kDa

Gen-ID: 3987

UniProt: P48059