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alpha KGDHC Antikörper

alphaKGDHC Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7011083
  • Target Alle alpha KGDHC (alphaKGDHC) Antikörper anzeigen
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Reaktivität
    • 26
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 25
    • 1
    Kaninchen
    Klonalität
    • 25
    • 1
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    Dieser alpha KGDHC Antikörper ist unkonjugiert
    Applikation
    • 22
    • 14
    • 14
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human OGDH (NP_001003941.1).
    Isotyp
    IgG
    Top Product
    Discover our top product alphaKGDHC Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Andere Bezeichnung
    OGDH (alphaKGDHC Produkte)
    Hintergrund
    This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht

    Observed_MW: 116 kDa

    Calculated_MW: 48 kDa/115 kDa

    Gen-ID
    4967
    UniProt
    Q02218
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