Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CCM2 Antikörper

CCM2 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7262401
  • Target Alle CCM2 Antikörper anzeigen
    CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
    Reaktivität
    • 26
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 18
    • 7
    • 1
    Kaninchen
    Klonalität
    • 22
    • 4
    Polyklonal
    Konjugat
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCM2 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CCM2 (NP_113631.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CCM2 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
    Andere Bezeichnung
    CCM2 (CCM2 Produkte)
    Synonyme
    C7orf22 antikoerper, OSM antikoerper, malcavernin antikoerper, CCM2 antikoerper, BC029157 antikoerper, TUF2 antikoerper, vtn antikoerper, zgc:110233 antikoerper, CCM2 scaffolding protein antikoerper, cerebral cavernous malformation 2 antikoerper, malcavernin antikoerper, CCM2 antikoerper, Ccm2 antikoerper, LOC100304744 antikoerper, ccm2 antikoerper
    Hintergrund
    This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
    Gen-ID
    83605
    UniProt
    Q9BSQ5
    Pathways
    Cell-Cell Junction Organization
Sie sind hier:
Kundenservice