NPHP1 Antikörper

Produktnummer ABIN7262561

Produktdetails anti-NPHP1 Antikörper

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPHP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human NPHP1 (NP_001121651.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NPHP1

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Andere Bezeichnung: NPHP1 (NPHP1 Produkte)

Synonyme: JBTS4 antikoerper, NPH1 antikoerper, SLSN1 antikoerper, nephrocystin-1 antikoerper, NPHP1 antikoerper, im:7162391 antikoerper, wu:fi59g07 antikoerper, zgc:152930 antikoerper, Nphp1 antikoerper, nephrocystin 1 antikoerper, nephronophthisis 1 (juvenile) homolog (human) antikoerper, nephronophthisis 1 (juvenile) L homeolog antikoerper, nephronophthisis 1 antikoerper, nephrocystin-1 antikoerper, NPHP1 antikoerper, Nphp1 antikoerper, nphp1.L antikoerper, nphp1 antikoerper, LOC100725987 antikoerper

Hintergrund: This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 83 kDa

Calculated_MW: 69 kDa/77 kDa/83 kDa

Gen-ID: 4867

UniProt: O15259