PPM1A Antikörper
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- Target Alle PPM1A Antikörper anzeigen
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPM1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PPM1A (NP_066283.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PPM1A Primärantikörper
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anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) antibody
PPM1A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 202-382) antibodyPPM1A Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 7F12H6 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 4E11 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-383) antibodyPPM1A Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 4E11 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 107-156) antibodyPPM1A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Huhn, Schwein, Fledermaus, Hamster, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) antibodyPPM1A Reaktivität: Human, Maus WB, ELISA, IP Wirt: Maus Monoclonal p6c7 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal p6c7 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- Andere Bezeichnung
- PPM1A (PPM1A Produkte)
- Hintergrund
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
- Molekulargewicht
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Observed_MW: 42 kDa
Calculated_MW: 35 kDa/42 kDa/51 kDa
- Gen-ID
- 5494
- UniProt
- P35813
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