MUS81 Antikörper

Produktnummer ABIN7262745

Produktdetails anti-MUS81 Antikörper

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUS81 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human MUS81 (NP_079404.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Andere Bezeichnung: MUS81 (MUS81 Produkte)

Synonyme: CG3026 antikoerper, Dmel\\CG3026 antikoerper, EG:BACR7A4.16 antikoerper, MUS81 antikoerper, GB15332 antikoerper, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antikoerper, ATMUS81 antikoerper, F6I18.220 antikoerper, F6I18_220 antikoerper, MMS AND UV SENSITIVE 81 antikoerper, SLX3 antikoerper, slx3 antikoerper, 1200008A18Rik antikoerper, AI182501 antikoerper, AW045863 antikoerper, wu:fc26g01 antikoerper, zgc:66489 antikoerper, zgc:91801 antikoerper, CG3026 gene product from transcript CG3026-RA antikoerper, MUS81 structure-specific endonuclease subunit antikoerper, crossover junction endonuclease MUS81 antikoerper, Restriction endonuclease, type II-like superfamily protein antikoerper, Mus81p antikoerper, Holliday junction resolvase subunit Mus81 antikoerper, MUS81 protein antikoerper, hypothetical protein antikoerper, mus81 antikoerper, MUS81 antikoerper, LOC725951 antikoerper, Mus81 antikoerper, CAALFM_C600540WA antikoerper

Hintergrund: This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

Gen-ID: 80198

UniProt: Q96NY9

Pathways: DNA Reparatur