PARN Antikörper
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- Target Alle PARN Antikörper anzeigen
- PARN (Poly A Specific Ribonuclease (PARN))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PARN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PARN (NP_002573.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PARN Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PARN (Poly A Specific Ribonuclease (PARN))
- Andere Bezeichnung
- PARN (PARN Produkte)
- Synonyme
- parn-A antikoerper, xparn antikoerper, DAN antikoerper, RGD1565449 antikoerper, zgc:56067 antikoerper, 1200003I18Rik antikoerper, poly(A)-specific ribonuclease L homeolog antikoerper, poly(A)-specific ribonuclease antikoerper, poly(A)-specific ribonuclease (deadenylation nuclease) antikoerper, parn.L antikoerper, PARN antikoerper, Parn antikoerper, parn antikoerper
- Hintergrund
- The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 73 kDa
Calculated_MW: 52 kDa/66 kDa/67 kDa/73 kDa
- Gen-ID
- 5073
- UniProt
- O95453
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