PDE6B Antikörper
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- Target Alle PDE6B Antikörper anzeigen
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE6B Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PDE6B (NP_001138763.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PDE6B Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
- Andere Bezeichnung
- PDE6B (PDE6B Produkte)
- Synonyme
- CSNB3 antikoerper, CSNBAD2 antikoerper, PDEB antikoerper, RP40 antikoerper, rd1 antikoerper, PDBS antikoerper, RCD-1 antikoerper, Pdeb antikoerper, r antikoerper, rd antikoerper, rd-1 antikoerper, rd10 antikoerper, phosphodiesterase 6B antikoerper, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antikoerper, PDE6B antikoerper, Pde6b antikoerper
- Hintergrund
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gen-ID
- 5158
- UniProt
- P35913
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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