TLK1 Antikörper (AA 458-560)

Produktnummer ABIN701155

Produktdetails anti-TLK1 Antikörper

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Bindungsspezifität: AA 458-560

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TLK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Andere Bezeichnung: TLK1 (TLK1 Produkte)

Synonyme: PKU-beta antikoerper, 4930545J15Rik antikoerper, fe11e12 antikoerper, si:dkey-251e16.4 antikoerper, tlk1 antikoerper, wu:fe11e12 antikoerper, TLK1 antikoerper, fb76h12 antikoerper, si:dkey-88m1.1 antikoerper, wu:fb76h12 antikoerper, DKFZp459L163 antikoerper, tousled like kinase 1 antikoerper, tousled-like kinase 1 antikoerper, tousled-like kinase 1b antikoerper, tousled like kinase 1 like antikoerper, serine/threonine-protein kinase TOUSLED antikoerper, tousled-like kinase 1a antikoerper, Serine/threonine-protein kinase tousled-like 1 antikoerper, TLK1 antikoerper, Tlk1 antikoerper, tlk1b antikoerper, TLK1L antikoerper, LOC542181 antikoerper, tlk1a antikoerper, tlk1 antikoerper, tlk-1 antikoerper

Hintergrund:

Synonyms: PKU beta, serine threonine protein kinase, Serine/threonine protein kinase tousled like 1, TLK1, Tousled like kinase 1.

Background: TLK1 is a nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. TLK1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin.

Gen-ID: 9874