RNF7 Antikörper

Produktnummer ABIN7263303

Produktdetails anti-RNF7 Antikörper

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF7 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human RNF7 (NP_055060.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:20-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Andere Bezeichnung: RNF7 (RNF7 Produkte)

Synonyme: CKBBP1 antikoerper, ROC2 antikoerper, SAG antikoerper, Rbx2 antikoerper, ring finger protein 7 antikoerper, RNF7 antikoerper, Rnf7 antikoerper

Hintergrund: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gen-ID: 9616

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity