GLUD1 Antikörper

Produktnummer ABIN7263621

Produktdetails anti-GLUD1 Antikörper

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUD1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human GLUD1 (NP_005262.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GLUD1

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Andere Bezeichnung: GLUD1 (GLUD1 Produkte)

Synonyme: GDH antikoerper, gdh1 antikoerper, GDH 1 antikoerper, glud1 antikoerper, GLUD1 antikoerper, cb719 antikoerper, wu:fb16e02 antikoerper, wu:fb58f12 antikoerper, wu:fe37f03 antikoerper, wu:fj43f02 antikoerper, zgc:192851 antikoerper, zgc:55630 antikoerper, GDH1 antikoerper, GLUD antikoerper, AI118167 antikoerper, Gdh-X antikoerper, Glud antikoerper, Gludl antikoerper, Ac2-281 antikoerper, Gdh1 antikoerper, Gludeha antikoerper, MRG-2 antikoerper, GLUTAMATE DECARBOXYLASE 1 antikoerper, GLUTAMATE DEHYDROGENASE 1 antikoerper, MRG7.13 antikoerper, MRG7_13 antikoerper, glutamate dehydrogenase 1 antikoerper, C2H1orf130 antikoerper, legdh1 antikoerper, cb622 antikoerper, wu:fc33g09 antikoerper, wu:fc66a10 antikoerper, zgc:77186 antikoerper, glutamate dehydrogenase 1 antikoerper, glutamate dehydrogenase 1 S homeolog antikoerper, glutamate dehydrogenase 1, mitochondrial antikoerper, glutamate dehydrogenase 1b antikoerper, glutamate dehydrogenase antikoerper, non-compact myelin associated protein antikoerper, glutamate dehydrogenase 1a antikoerper, GLUD1 antikoerper, GDH1 antikoerper, glud1 antikoerper, glud1.S antikoerper, LOC693461 antikoerper, glud1b antikoerper, Glud1 antikoerper, HACJB3_RS00320 antikoerper, LOC100587725 antikoerper, NCMAP antikoerper, gdh1 antikoerper, glud1a antikoerper

Hintergrund: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

Gen-ID: 2746

UniProt: P00367

Pathways: Positive Regulation of Peptide Hormone Secretion, Warburg Effekt