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GTF2A2 Antikörper

GTF2A2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7263683
  • Target Alle GTF2A2 Antikörper anzeigen
    GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))
    Reaktivität
    • 14
    • 9
    • 9
    Human
    Wirt
    • 12
    • 2
    Kaninchen
    Klonalität
    • 13
    • 1
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GTF2A2 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human GTF2A2 (NP_004483.1).
    Isotyp
    IgG
    Top Product
    Discover our top product GTF2A2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))
    Andere Bezeichnung
    GTF2A2 (GTF2A2 Produkte)
    Hintergrund
    Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
    Molekulargewicht

    Observed_MW: 12 kDa

    Calculated_MW: 12 kDa

    Gen-ID
    2958
    UniProt
    P52657
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