DPM1 Antikörper

Produktnummer ABIN7263775

Produktdetails anti-DPM1 Antikörper

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPM1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DPM1 (NP_003850.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DPM1

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Andere Bezeichnung: DPM1 (DPM1 Produkte)

Synonyme: DPM1 antikoerper, zgc:101018 antikoerper, MGC114892 antikoerper, AI118379 antikoerper, AI194292 antikoerper, CDGIE antikoerper, MPDS antikoerper, DPMS antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antikoerper, dolichyl-phosphate mannosyltransferase subunit 1, catalytic antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog antikoerper, dolichol-phosphate (beta-D) mannosyltransferase 1 antikoerper, dpm1 antikoerper, DPM1 antikoerper, dpm1.S antikoerper, Dpm1 antikoerper

Hintergrund: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.

Gen-ID: 8813

UniProt: O60762

Pathways: Inositol Metabolic Process