C79673 antikoerper, Kindlin3 antikoerper, RGD1310168 antikoerper, MGC69069 antikoerper, MGC88900 antikoerper, KIND3 antikoerper, MIG-2 antikoerper, MIG2B antikoerper, UNC112C antikoerper, URP2 antikoerper, URP2SF antikoerper, zgc:64101 antikoerper, fermitin family member 3 antikoerper, fermitin family member 3 L homeolog antikoerper, fermitin family member 3b antikoerper, Fermt3 antikoerper, fermt3.L antikoerper, fermt3 antikoerper, FERMT3 antikoerper, fermt3b antikoerper
Hintergrund
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.