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FLT3 Antikörper

FLT3 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7012052
  • Target Alle FLT3 Antikörper anzeigen
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Reaktivität
    • 144
    • 57
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 143
    • 17
    • 6
    • 1
    Kaninchen
    Klonalität
    • 144
    • 23
    Polyklonal
    Konjugat
    • 67
    • 14
    • 10
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser FLT3 Antikörper ist unkonjugiert
    Applikation
    • 113
    • 69
    • 42
    • 42
    • 37
    • 21
    • 19
    • 12
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FLT3
    Isotyp
    IgG
    Top Product
    Discover our top product FLT3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Andere Bezeichnung
    FLT3 (FLT3 Produkte)
    Synonyme
    FLT3 antikoerper, B230315G04 antikoerper, CD135 antikoerper, Flk-2 antikoerper, Flk2 antikoerper, Flt-3 antikoerper, Ly72 antikoerper, wmfl antikoerper, FLK-2 antikoerper, FLK2 antikoerper, STK1 antikoerper, fms related tyrosine kinase 3 antikoerper, FMS-like tyrosine kinase 3 antikoerper, fms-related tyrosine kinase 3 antikoerper, FLT3 antikoerper, Flt3 antikoerper
    Hintergrund
    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
    Molekulargewicht

    Observed_MW: 113 kDa

    Calculated_MW: 108 kDa/112 kDa

    Gen-ID
    2322
    UniProt
    P36888
    Pathways
    RTK Signalweg
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