MBNL1 Antikörper
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- Target Alle MBNL1 Antikörper anzeigen
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MBNL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MBNL1 (NP_066368.2).
- Isotyp
- IgG
- Top Product
- Discover our top product MBNL1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- Andere Bezeichnung
- MBNL1 (MBNL1 Produkte)
- Synonyme
- MBNL1 antikoerper, zgc:153954 antikoerper, Mbnl antikoerper, mKIAA0428 antikoerper, EXP antikoerper, EXP35 antikoerper, EXP40 antikoerper, EXP42 antikoerper, MBNL antikoerper, muscleblind like splicing regulator 1 antikoerper, muscleblind-like splicing regulator 1 antikoerper, muscleblind like splicing factor 1 antikoerper, MBNL1 antikoerper, mbnl1 antikoerper, Mbnl1 antikoerper
- Hintergrund
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
- Molekulargewicht
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Observed_MW: 42 kDa
Calculated_MW: 33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa
- Gen-ID
- 4154
- UniProt
- Q9NR56
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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