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MBNL1 Antikörper

MBNL1 Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7264101
  • Target Alle MBNL1 Antikörper anzeigen
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    Reaktivität
    • 45
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 38
    • 6
    • 1
    Kaninchen
    Klonalität
    • 39
    • 6
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBNL1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 25
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MBNL1 (NP_066368.2).
    Isotyp
    IgG
    Top Product
    Discover our top product MBNL1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    Andere Bezeichnung
    MBNL1 (MBNL1 Produkte)
    Synonyme
    MBNL1 antikoerper, zgc:153954 antikoerper, Mbnl antikoerper, mKIAA0428 antikoerper, EXP antikoerper, EXP35 antikoerper, EXP40 antikoerper, EXP42 antikoerper, MBNL antikoerper, muscleblind like splicing regulator 1 antikoerper, muscleblind-like splicing regulator 1 antikoerper, muscleblind like splicing factor 1 antikoerper, MBNL1 antikoerper, mbnl1 antikoerper, Mbnl1 antikoerper
    Hintergrund
    This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
    Molekulargewicht

    Observed_MW: 42 kDa

    Calculated_MW: 33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa

    Gen-ID
    4154
    UniProt
    Q9NR56
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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