NOTCH4 Antikörper
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- Target Alle NOTCH4 Antikörper anzeigen
- NOTCH4 (Notch 4 (NOTCH4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOTCH4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human NOTCH4 (NP_004548.3).
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH4 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NOTCH4 (Notch 4 (NOTCH4))
- Andere Bezeichnung
- NOTCH4 (NOTCH4 Produkte)
- Synonyme
- INT3 antikoerper, NOTCH3 antikoerper, Int-3 antikoerper, Int3 antikoerper, N4 antikoerper, Notch4 antikoerper, notch 4 antikoerper, neurogenic locus notch homolog protein 4 antikoerper, NOTCH4 antikoerper, Notch4 antikoerper, LOC100712850 antikoerper
- Hintergrund
- This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molekulargewicht
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Observed_MW: 88 kDa
Calculated_MW: 39 kDa/61 kDa/209 kDa
- Gen-ID
- 4855
- UniProt
- Q99466
- Pathways
- Notch Signalweg
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