PSMB3 Antikörper

Produktnummer ABIN7264968

Produktdetails anti-PSMB3 Antikörper

Target: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PSMB3 (NP_002786.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PSMB3

Target: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Andere Bezeichnung: PSMB3 (PSMB3 Produkte)

Synonyme: HC10-II antikoerper, AL033320 antikoerper, C10-II antikoerper, PSB3 antikoerper, psmb3 antikoerper, wu:fb11d10 antikoerper, wu:fu88b08 antikoerper, zgc:56374 antikoerper, DDBDRAFT_0190542 antikoerper, DDBDRAFT_0232932 antikoerper, DDB_0190542 antikoerper, DDB_0232932 antikoerper, proteasome subunit beta 3 antikoerper, proteasome (prosome, macropain) subunit, beta type 3 antikoerper, proteasome subunit C10-11 antikoerper, proteasome subunit beta type-3 antikoerper, proteasome subunit beta 3 S homeolog antikoerper, 20S proteasome subunit beta-3 antikoerper, PSMB3 antikoerper, Psmb3 antikoerper, LOC100135869 antikoerper, LOC399377 antikoerper, psmb3.S antikoerper, psmb3 antikoerper, psmB3 antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants

Molekulargewicht:

Observed_MW: 23 kDa

Calculated_MW: 22 kDa

Gen-ID: 5691

UniProt: P49720

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Cell RedoxHomeostasis, Lipid Metabolism