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CDK1 Antikörper (pTyr15)

CDK1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7265020
  • Target Alle CDK1 Antikörper anzeigen
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    Bindungsspezifität
    • 34
    • 23
    • 22
    • 20
    • 17
    • 16
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr15
    Reaktivität
    • 299
    • 170
    • 106
    • 40
    • 33
    • 31
    • 25
    • 20
    • 14
    • 14
    • 12
    • 11
    • 10
    • 9
    • 9
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 247
    • 61
    Kaninchen
    Klonalität
    • 235
    • 73
    Polyklonal
    Konjugat
    • 167
    • 21
    • 14
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDK1 Antikörper ist unkonjugiert
    Applikation
    • 249
    • 107
    • 59
    • 57
    • 54
    • 53
    • 48
    • 44
    • 42
    • 20
    • 19
    • 16
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Phosphorylated antibody
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around Y15 of human CDK1 (NP_001777.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CDK1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    Andere Bezeichnung
    CDK1 (CDK1 Produkte)
    Hintergrund
    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 34 kDa

    Calculated_MW: 27 kDa/34 kDa

    Gen-ID
    983
    UniProt
    P06493
    Pathways
    Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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