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SMC1A Antikörper (pSer957)

SMC1A Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7265084
  • Target Alle SMC1A Antikörper anzeigen
    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
    Bindungsspezifität
    • 24
    • 16
    • 16
    • 14
    • 12
    • 12
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer957
    Reaktivität
    • 136
    • 55
    • 23
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 116
    • 15
    • 4
    • 1
    Kaninchen
    Klonalität
    • 103
    • 33
    Polyklonal
    Konjugat
    • 68
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SMC1A Antikörper ist unkonjugiert
    Applikation
    • 102
    • 43
    • 29
    • 29
    • 28
    • 23
    • 20
    • 12
    • 9
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    Phosphorylated antibody
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around S957 of human SMC1A (NP_006297.2).
    Isotyp
    IgG
    Top Product
    Discover our top product SMC1A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:20-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
    Andere Bezeichnung
    SMC1A (SMC1A Produkte)
    Synonyme
    CDLS2 antikoerper, DXS423E antikoerper, SB1.8 antikoerper, SMC1 antikoerper, SMC1L1 antikoerper, SMC1alpha antikoerper, SMCB antikoerper, SMC-1A antikoerper, NV15570 antikoerper, 5830426I24Rik antikoerper, Sb1.8 antikoerper, Smc1 antikoerper, Smc1alpha antikoerper, Smc1l1 antikoerper, Smcb antikoerper, mKIAA0178 antikoerper, smc1 antikoerper, smc1a antikoerper, smc1l1 antikoerper, xSMC1 antikoerper, smc1aa antikoerper, structural maintenance of chromosomes 1A antikoerper, structural maintenance of chromosomes 1A b antikoerper, structural maintenance of chromosomes 1A L homeolog antikoerper, SMC1A antikoerper, smc1a antikoerper, Smc1a antikoerper, smc1ab antikoerper, smc1a.L antikoerper
    Hintergrund
    Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molekulargewicht

    Observed_MW: 160 kDa

    Calculated_MW: 143 kDa

    Gen-ID
    8243
    UniProt
    Q14683
    Pathways
    Stem Cell Maintenance
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