Separase Antikörper (pSer1126)

Produktnummer ABIN7265212

Produktdetails anti-Separase Antikörper

Target: Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))

Bindungsspezifität: pSer1126

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Separase Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:20-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Separase

Target: Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))

Andere Bezeichnung: ESPL1 (ESPL1 Produkte)

Synonyme: ESP1 antikoerper, SEPA antikoerper, mp:zf637-3-001691 antikoerper, AL024103 antikoerper, AU045071 antikoerper, Cerp antikoerper, PRCE antikoerper, SSE antikoerper, extra spindle pole bodies like 1, separase antikoerper, extra spindle poles like 1 antikoerper, extra spindle pole bodies 1, separase antikoerper, ESPL1 antikoerper, espl1 antikoerper, Espl1 antikoerper

Hintergrund: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

Gen-ID: 9700

UniProt: Q14674