YAP1 Antikörper (pSer127)
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- Target Alle YAP1 Antikörper anzeigen
- YAP1 (Yes-Associated Protein 1 (YAP1))
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Bindungsspezifität
- pSer127
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser YAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
- Isotyp
- IgG
- Top Product
- Discover our top product YAP1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000 IF 1:20-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- YAP1 (Yes-Associated Protein 1 (YAP1))
- Andere Bezeichnung
- YAP1 (YAP1 Produkte)
- Hintergrund
- This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molekulargewicht
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Observed_MW: 60 kDa/68 kDa
Calculated_MW: 36 kDa/48 kDa/49 kDa/50 kDa/52 kDa/53 kDa/54 kDa
- Gen-ID
- 10413
- UniProt
- P46937
- Pathways
- MAPK Signalweg, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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