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beta Catenin Antikörper (pSer33, pSer37, pThr41)

Name: beta Catenin Antikörper (pSer33, pSer37, pThr41)
Brand: antibodies-online
SKU: ABIN7265240
Price: 590 EUR
Availability: InStock

CATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of 293T cells using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody. (beta Catenin Antikörper (pSer33, pSer37, pThr41))

Immunohistochemistry of paraffin-embedded Human colon carcinoma using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens). (beta Catenin Antikörper (pSer33, pSer37, pThr41))

IHC (p)

Immunohistochemistry of paraffin-embedded Human skin using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens). (beta Catenin Antikörper (pSer33, pSer37, pThr41))

IHC (p)

Immunohistochemistry of paraffin-embedded Rat skin using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens). (beta Catenin Antikörper (pSer33, pSer37, pThr41))

IHC (p)

Immunohistochemistry of paraffin-embedded Mouse kidney using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens). (beta Catenin Antikörper (pSer33, pSer37, pThr41))

IHC (p)

Immunohistochemistry of paraffin-embedded Human lung cancer using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens). (beta Catenin Antikörper (pSer33, pSer37, pThr41))

IHC (p)

6 Abbildungen

Produktnummer ABIN7265240

Datenblatt (PDF)

Target Alle beta Catenin (CATNB) Antikörper anzeigen

beta Catenin (CATNB) (Catenin, beta (CATNB))
Bindungsspezifität
48

27

25

25

23

19

17

17

16

16

16

15

10

8

7

7

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer33, pSer37, pThr41
Reaktivität
345

255

233

28

23

22

18

17

7

5

5

5

1

1

1

1

1

1

1

1
Human, Maus, Ratte
Wirt
286

59

4

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
279

72
Polyklonal
Konjugat
131

22

11

10

9

9

9

9

9

9

9

9

9

9

9

8

8

7

7

7

7

7

4

4

4

4

4

4

1

1

1
Dieser beta Catenin Antikörper ist unkonjugiert
Applikation
215

159

120

118

80

64

64

52

35

32

24

9

7

4

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale

Phosphorylated antibody

Aufreinigung

Affinity purification

Immunogen

A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).

Isotyp

IgG

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Applikationshinweise

WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung

beta-catenin (CATNB Produkte)

Synonyme

Bfc antikoerper, Catnb antikoerper, Mesc antikoerper, CTNNB antikoerper, MRD19 antikoerper, armadillo antikoerper, ctnnb antikoerper, id:ibd2058 antikoerper, wu:fb73e10 antikoerper, wu:fi81c06 antikoerper, wu:fk25h01 antikoerper, beta-catenin antikoerper, ctnnb1 antikoerper, CHBCAT antikoerper, catenin (cadherin associated protein), beta 1 antikoerper, catenin beta 1 antikoerper, catenin (cadherin-associated protein), beta 1 antikoerper, catenin beta 1 L homeolog antikoerper, Ctnnb1 antikoerper, CTNNB1 antikoerper, ctnnb1 antikoerper, ctnnb1.L antikoerper

Hintergrund

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 85 kDa
Calculated_MW: 9 kDa/85 kDa

Gen-ID

1499

UniProt

P35222

Pathways

Peptide Hormone Metabolism