POLR2A/RPB1 Antikörper (pSer5)

Produktnummer ABIN7265278

Produktdetails anti-POLR2A/RPB1 Antikörper

Target: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Bindungsspezifität: pSer5

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2A/RPB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S5 of human POLR2A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POLR2A/RPB1

Target: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Andere Bezeichnung: POLR2A (POLR2A Produkte)

Synonyme: NCU02103.1 antikoerper, 19.m02399 antikoerper, POLR2A antikoerper, 220kDa antikoerper, Rpb1 antikoerper, Rpo2-1 antikoerper, POLR2 antikoerper, POLRA antikoerper, RPB1 antikoerper, RPBh1 antikoerper, RPO2 antikoerper, RPOL2 antikoerper, RpIILS antikoerper, hRPB220 antikoerper, hsRPB1 antikoerper, DNA-directed RNA polymerase II largest subunit antikoerper, DNA-directed RNA polymerase II subunit RPB1 antikoerper, RNA polymerase II large subunit Rpb1 antikoerper, RNA polymerase II subunit A antikoerper, DNA-directed RNA polymerase II largest subunit, putative antikoerper, polymerase (RNA) II (DNA directed) polypeptide A, 220kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide A antikoerper, NCU02103 antikoerper, BBOV_I003360 antikoerper, EDI_169920 antikoerper, CMU_000800 antikoerper, SJAG_01713 antikoerper, MGYG_01527 antikoerper, POLR2A antikoerper, TP03_0185 antikoerper, EBI_22514 antikoerper, CGB_E5020W antikoerper, polr2a antikoerper, Polr2a antikoerper

Hintergrund: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Molekulargewicht:

Observed_MW: 260 kDa

Calculated_MW: 63 kDa/217 kDa

Gen-ID: 5430

UniProt: P24928

Pathways: Regulatorische RNA Pathways