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CD8B Antikörper

CD8B Reaktivität: Ratte FACS, WB, IP, IHC (fro), Func Wirt: Maus Monoclonal 341 unconjugated
Produktnummer ABIN7013937
  • Target Alle CD8B Antikörper anzeigen
    CD8B (CD8b Molecule (CD8B))
    Reaktivität
    • 76
    • 31
    • 21
    • 17
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 76
    • 45
    • 23
    Maus
    Klonalität
    • 78
    • 65
    • 1
    Monoklonal
    Konjugat
    • 60
    • 18
    • 17
    • 13
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD8B Antikörper ist unkonjugiert
    Applikation
    • 78
    • 77
    • 45
    • 27
    • 20
    • 16
    • 13
    • 13
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Spezifität
    The mouse monoclonal antibody 341 (also known as 34.1) recognizes rat CD8b, the 32-34 kDa beta chain of the CD8 coreceptor (extracellular epitope), expressed on T cell subsets and some other cell types, such as macrophages.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Endotoxin-Niveau
    Low Endotoxin
    Immunogen
    CD8 positive Wistar rat splenic T cell hybridomas
    Klon
    341
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD8B Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Functional application: In vitro stimulation, in vivo depletion.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD8B (CD8b Molecule (CD8B))
    Andere Bezeichnung
    CD8b (CD8B Produkte)
    Synonyme
    Cd8b antikoerper, Ly-3 antikoerper, Ly-C antikoerper, Lyt-3 antikoerper, CD8B1 antikoerper, LEU2 antikoerper, LY3 antikoerper, LYT3 antikoerper, P37 antikoerper, Cd8b1 antikoerper, CD8b molecule antikoerper, CD8 antigen, beta chain 1 antikoerper, Cd8b antikoerper, CD8B antikoerper, Cd8b1 antikoerper
    Hintergrund
    CD8b molecule,The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages, mast cells, and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.,Ly-3, Ly-C, Lyt-3
    Gen-ID
    926
    UniProt
    P10966
    Pathways
    T-Zell Rezeptor Signalweg
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