CD8B Antikörper
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- Target Alle CD8B Antikörper anzeigen
- CD8B (CD8b Molecule (CD8B))
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8B Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Spezifität
- The mouse monoclonal antibody 341 (also known as 34.1) recognizes rat CD8b, the 32-34 kDa beta chain of the CD8 coreceptor (extracellular epitope), expressed on T cell subsets and some other cell types, such as macrophages.
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Endotoxin-Niveau
- Low Endotoxin
- Immunogen
- CD8 positive Wistar rat splenic T cell hybridomas
- Klon
- 341
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD8B Primärantikörper
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anti-CD8b Molecule (CD8B) antibody
CD8B Reaktivität: Human, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibodyCD8B Reaktivität: Ratte FACS, WB, IP, IHC (fro) Wirt: Maus Monoclonal 341 unconjugated
anti-CD8b Molecule (CD8B) antibody (FITC)CD8B Reaktivität: Ratte FACS Wirt: Maus Monoclonal 341 FITC
anti-CD8b Molecule (CD8B) antibody (PE)CD8B Reaktivität: Ratte FACS Wirt: Maus Monoclonal 341 PE
anti-CD8b Molecule (CD8B) (AA 51-150) antibodyCD8B Reaktivität: Human WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibody (PE)CD8B Reaktivität: Maus FACS Wirt: Ratte Monoclonal H35-17-2 PE
anti-CD8b Molecule (CD8B) (AA 1-243) antibodyCD8B Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibody (FITC)CD8B Reaktivität: Huhn FACS Wirt: Maus Monoclonal EP42 FITC
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- Applikationshinweise
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Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: In vitro stimulation, in vivo depletion. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Andere Bezeichnung
- CD8b (CD8B Produkte)
- Synonyme
- Cd8b antikoerper, Ly-3 antikoerper, Ly-C antikoerper, Lyt-3 antikoerper, CD8B1 antikoerper, LEU2 antikoerper, LY3 antikoerper, LYT3 antikoerper, P37 antikoerper, Cd8b1 antikoerper, CD8b molecule antikoerper, CD8 antigen, beta chain 1 antikoerper, Cd8b antikoerper, CD8B antikoerper, Cd8b1 antikoerper
- Hintergrund
- CD8b molecule,The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages, mast cells, and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.,Ly-3, Ly-C, Lyt-3
- Gen-ID
- 926
- UniProt
- P10966
- Pathways
- T-Zell Rezeptor Signalweg
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